Falls in Parkinson Disease

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چکیده

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Falls in Parkinson Disease

Falls are a major risk for Parkinson disease patients (PD). We sought to understand why patients fall. In one study we followed 404 PD patients for a year, 204 of who fell at least once. We did not distinguish between single and recurrent fallers. In a second study we followed 249 different patients for a year, 205 of whom fell once and 44 fell more than once (recurrent fallers). In the first s...

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Predicting Falls in Parkinson Disease Patients

Background: Falls are a major risk for Parkinson disease patients (PD). Single falls, in older people may be related to the underlying disease or may be accidental. Recurrent falls are more likely to be related to the underlying disease. Objectives: To predict falls in patients with Parkinson disease. Patients and Methods: Between July 1, 2011 and June 30, 2012 we examined 452 persons with PD i...

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Can fall of blood pressure prevent falls in Parkinson disease?

Idiopathic Parkinson disease (PD) is ana-synucleinopathy, one of several proteinopathies characterized by intracellular and extracellular accumulation of abnormal filament proteins. Relentless progression of neuropathologic changes, consisting of a-synuclein-positive Lewy bodies and Lewy neurites, and widespread neuronal loss closely correlate with clinical worsening of motor and nonmotor PD sy...

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Predicting Falls in Parkinson Disease: What Is the Value of Instrumented Testing in OFF Medication State?

BACKGROUND Falls are a common complication of advancing Parkinson's disease (PD). Although numerous risk factors are known, reliable predictors of future falls are still lacking. The objective of this prospective study was to investigate clinical and instrumented tests of balance and gait in both OFF and ON medication states and to verify their utility in the prediction of future falls in PD pa...

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Droxidopa and Reduced Falls in a Trial of Parkinson Disease Patients With Neurogenic Orthostatic Hypotension

OBJECTIVES Droxidopa is a prodrug of norepinephrine indicated for the treatment of orthostatic dizziness, lightheadedness, or the "feeling that you are about to black out" in adult patients with symptomatic neurogenic orthostatic hypotension caused by primary autonomic failure including Parkinson disease (PD). The objective of this study was to compare fall rates in PD patients with symptomatic...

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ژورنال

عنوان ژورنال: Journal of Alzheimer’s Disease & Parkinsonism

سال: 2016

ISSN: 2161-0460

DOI: 10.4172/2161-0460.1000248